Network Analysis

Explore gene and protein interaction networks in vitiligo research

GGI Network (Differential Genes)

Combined intersection gene-gene interaction network of differentially expressed genes from various vitiligo phenotypes (Lesional, Non-Lesional, and Peri-Lesional). The edges represent co-expression, while unconnected network groups indicate independent expressions.

Combined DEGs
Co-expression
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PPI Network (Protein Targets)

Combined protein-protein interaction network of manually curated protein targets for vitiligo. This network is a refined subset of the original network from Malhotra et al., 2017, filtered based on degree and crystal structure availability in PDB.

Protein Interactions
Crystal Structures
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Disease Intersection Networks

Multiple Sclerosis Intersection

Comorbidity network of DEGs common to Multiple Sclerosis and Vitiligo. Network edges reconstructed via GeneMania represent co-expression, physical expression, and shared protein domains.

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Rheumatoid Arthritis Intersection

Comorbidity network of DEGs shared between Rheumatoid Arthritis and Vitiligo. Network connections show co-expression, physical expression, and shared protein domains via GeneMania.

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Psoriasis Intersection

Comorbidity network of DEGs common to Psoriasis and Vitiligo. Network edges from GeneMania indicate co-expression, physical expression, and shared protein domains.

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